Designing and Conducting Pragmatic Randomised Controlled Trials

Description:

Pragmatic Randomised Controlled Trial (RCTs) are the ‘gold standard’ test for evaluating whether a new intervention is better than an existing one and are routinely used in both real-world healthcare and public health settings. Academics working in the Bristol Trials Centre (BTC) and the University of Bristol (including those who are tutors on this course) have all been at the forefront of designing and implementing high quality pragmatic RCTs for this purpose.

This course aims to provide an understanding of the essentials of designing, conducting and analysing pragmatic randomised controlled trials (RCTs). The course examines RCTs evaluating health and public health interventions in primary, secondary and community settings with individual and cluster randomised designs. Please note this course does not go into lots of detail about regulatory approvals and research governance.

The course will specifically cover:

1. need for randomised trials;
2. design of trials;
3. randomisation;
4. sample size;
5. feasibility and pilot studies;
6. trial planning, resourcing and working with the NHS;
7. inclusion in trials;
8. trial initiation;
9. qualitative research in trials;
10. Patient and Public Involvement;
11. optimising trial recruitment;
12. trial conduct and closure;
13. protocol adherence and missing data;
14. cluster and public health trials, including in schools;
15. outcome assessment and Patient Reported Outcome Measures;
16. health economics overview;
17. primary and secondary trial analyses;
18. experience of being a Chief Investigator;
19. Clinical Trials Unit support for trialists; and
20. CRF and database design.

Cost:

£1,250

Website and registration:

Register for this course

Region:

South West

Keywords:

Randomized Control Trials (RCT)

Related publications and presentations from our eprints archive:

Randomized Control Trials (RCT)

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